Surveillance Of Antimicrobial Sensitivity Pattern Among The Patients Of Gastroenteritis In A Tertiary Teaching Care Hospital

Abstract

Gastroenteritis is the most common acquired infection nowadays. The gut microbiota is the source of most strategic pathogens which have the capacity to cause most deadly infections in critically ill patients and also healthy humans. So the aim of  this study was to record hospital acquired  and locality acquired accounts of  microbiota resistance to antibiotics, isolated from tissue samples from Department of Gastroenterology and Hepatobiliary Sciences of a hospital. From 100 tissue samples, 68 showed significant growth. The infection was excess in male than women and the infection chances was more in the age group of 41-60.  There were 10 different types of bacteria were identified. The predominant isolated bacteria was Klebsiella pneumoniae (20.58%) followed by Acinetobacter baumannii (17.64%), Proteus vulgaris (14.70%), Pseudomonas aeruginosa (14.70%), Enterococcus aerogenes (11.76%), Proteus mirabilis (7.35%), Klebsiella oxytoca (7.35%), Citrobacter freundii (2.94%), Escherichia coli (1.47%), Serrratia marcescens (1.47%). Escherichia coli had highest rate of resistance to antibiotics. All gram negative bacteria were highest resistant to Oxacillin, Amoxicillin, Co-trimoxazde, Cefuroxime, Clarithromycin, Azithromycin and Cefpodoxime whereas sensitive to Colistin, Tigecycline, Levofloxacin, Gentamycin, Amikacin, Imipenem and Ampicillin. We found that Klebsiella pneumoniae and Acinetobacter baumannii were most frequent microorganisms found in human gastrointestinal tract and were high rate of  resistance to Oxacillin and  susceptible to Colistin, Tigecycline, Levofloxacin, Gentamycin.