Evaluation of antioxidant and cytotoxic activity of marine red alga Scinaia furcellata (Turner) J.Agardh
Marine macro algae are important source of vast amounts of nutrients and bioactive components. These bioactive compounds are highly used in the treatment of diseases like cancer, AIDS, soreness, ache, arthritis, viral, bacterial, and fungal infections. In the present study, invitro antioxidant and cytotoxic activity of ethanol and ethylacetate extracts of Scinaia furcellata was evaluated. Antioxidant action was studied using 4 commonly used scavenging assays including DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical, hydroxyl radical, superoxide anion, ABTS radical and reducing power assay. Cytotoxic study against breast cancer cells MDA-MB-231 was studied by sulforhodamine B dye. Ethanol extract exhibited the maximum cytotoxic and antioxidant activity viz DPPH (113.53%), Hydroxyl (118.16%), ABTS (121.98%) Superoxide (113.16%) radical scavenging activity and also exhibits higher reducing activity.