Molecular detection of toxigenic and binary toxin producing Clostridium difficile in Antibiotic associated diarrhea: Laboratory based study in rural hospital in Western Maharashtra

  • Dr Priyanka M. Mane, Dr Satish R. Patil, Dr Makarand B. Mane, Dr Kailash Dathkhile, Dr Geeta S. Karande

Abstract

The dramatic change in the epidemiology of Clostridium difficile during recent years, in both frequency and severity, owing to the emergence of virulent strains like NAP1/BI/027 (North American Pulse Field type 1/Restriction Endonuclease Assay type BI/Ribotype 027) in North America ribotype 078 in Europe and ribotype 017 in Asia, has made C. difficile a public health concern. This strain was found to produce greater than 16 times toxin A and 23 times toxin B in addition to the binary toxin.

Published
2020-04-07
How to Cite
Dr Priyanka M. Mane, Dr Satish R. Patil, Dr Makarand B. Mane, Dr Kailash Dathkhile, Dr Geeta S. Karande. (2020). Molecular detection of toxigenic and binary toxin producing Clostridium difficile in Antibiotic associated diarrhea: Laboratory based study in rural hospital in Western Maharashtra. International Journal of Advanced Science and Technology, 29(5s), 1232 - 1238. Retrieved from http://sersc.org/journals/index.php/IJAST/article/view/8149