Delineation of Putamen from the Brain Magnetic Resonance Image for Parkinson Disease related Applications

  • G.L.N.Murthy,Sk. Gouse Mohiddin, .Saida Reddy,Y.Md.Imran, M.Durga Prasad Reddy

Abstract

Degeneration of the nerve cells responsible for body movement was noticed in Parkinson Disease (PD), resulting in slowdown in the movement and stiffness of the muscles. The symptoms need not be confined to these only, but may also vary in the way of talking or writing. The basal ganglia, responsible for initiating and coordinating motor related activities undergo atrophy due to this progressive disorder that is unnoticed in the initial stages. Various nerve cells constitute basal ganglia among which putamen that are responsible for regulating the motion. The current work is aimed at identifying the structural atrophy of Putamen by delineating the Putamen in the skull removed magnetic resonance (MR) image. Histogram modeling is used in pre-processing as well as estimation of threshold for extraction of non-brain. The results demonstrate a deviation from the normal size between normal and PD affected scans.

Keywords: Parkinson Disease (PD), Basal Ganglia, Putamen, Gaussian modeling, Histogram partitioning.

Published
2020-02-27
How to Cite
M.Durga Prasad Reddy, G. G. M. .Saida R. (2020). Delineation of Putamen from the Brain Magnetic Resonance Image for Parkinson Disease related Applications. International Journal of Advanced Science and Technology, 29(3), 3630 - 3635. Retrieved from http://sersc.org/journals/index.php/IJAST/article/view/5041
Section
Articles