Microwave Assisted Synthesis, Characterization and Anti-Microbial Activity of Transition Metal (II) Complexes with Bidentate Thiocarboxamide Ligand

Abstract

A series of bivalent transition metal complexes of Co(II), Ni(II) & Cu(II) with a monobasic bidentate (N & S donor) ligand N-(2-pyrimidyl)-quinoline-2-thiocarboxamide (L) having specific formula [ML₂Cl₂] have been synthesized  under environmentally benign manner using microwave irradiation in solvent-free conditions. The investigated complexes have been characterized by elemental analysis, magnetic and conductance measurements, IR and UV-visible spectral studies. All the synthesized complexes were non-electrolyte having octahedral  geometry. The antimicrobial study suggests that the metal complexes are better antibacterial agents as compared to the ligand and the antimicrobial activity trend of the investigated compounds is: