A study on Microbiological Profile and Antibiotic Susceptibility Pattern of the Organisms Isolated in Diabetic Foot

  • Dr Dangudubiyam Sree Usha, Dr Jayaprabha , Dr Vinod

Abstract

Aim: The present investigation mainly study the growth of aerobic organism in 100 diabetic foot ulcers, their antimicrobial profile and antibiotic sensitivity pattern were studied.

Methodology: Amongst 100 diabetic cases included in the present study most of them were in 5th and 6th decade, showing ulcers chiefly in right foot. Males were affected primelythan females in the ratio of 2:1. The study carried out in the Department of Microbiology at Sri Venkateswaraa Medical College and research centre from June 2012 to December 2014.

Results: 79 samples yielded aerobic bacterial growth in which 82% were mono microbial and 18% were polymicrobial. Remaining 21 samples did not yield any growth. Staphylococcus was predominant among the gram positive aerobes. Among gram negative aerobes, pseudomonas spp was the most common isolate (20.2%) followed by Klebsiella spp 15.1% and E.coli 12.6%. Citrobacter spp was the least common isolate (1.2%). They were all uniformly susceptible to Linezolid and about 81% of Staphylococcus aureus and 50% of CONS were sensitive to Vancomycin. The antibiotic susceptibility pattern of the gram negative isolates increase resistance to ampicillin, amoxyclav, co-triamoxazole and 3rd generation cephalosporins among the members of enterobacteriaceae. All the members of enterobacteriaceae were uniformly sensitive to gentamicin, amikacin and ciprofloxacin. 93% of Pseudomonas species were sensitive to imipenem and 56.2% were sensitive to ciprofloxacin and piperacillin+tazobactam.  40% of Acinetobacter species were sensitive to Imipenem followed by 20% to Co-trimoxazole, cefotaxime, cefatriazone, cefaperazone+sulbactam, amikacin, Gentamicin, piperacillin+tazobactam.

Conclusion: Diabetic foot infection are often caused by gram positive bacteria, staphylococcus species was the most predominant organism among gram positive cocci, Pseudomonas spp was the most common isolate among gram negative bacilli.

Published
2020-07-01
How to Cite
Dr Dangudubiyam Sree Usha, Dr Jayaprabha , Dr Vinod. (2020). A study on Microbiological Profile and Antibiotic Susceptibility Pattern of the Organisms Isolated in Diabetic Foot. International Journal of Advanced Science and Technology, 29(7), 13226 - 13237. Retrieved from http://sersc.org/journals/index.php/IJAST/article/view/29007
Section
Articles