Clinical Significance Of Some Immunological Indices In Children With Cardiomyop

Abstract

The article presents the results of studies of 104 patients with cardiomyopathies. As a result of
studies, it was found that in children with cardiomyopathies there is an increase in the levels of TNF-
α, VEGF, interleukins (IL-1, IL-6 and IL-8), which are directly dependent on the stage of cardiac failure
and hypoxia and determine the intensity of myocardial remodeling processes. In children with dilated
cardiomyopathy, there is a direct dependence of the degree of LV dilatation on the level of IL-1 and IL-
8, the final diastolic size on the concentration of IL-1, the final diastolic volume on the level of IL-8 and
the inverse relationship between the parameter of the exile fraction and IL-6 .