Phagocytic Activity of Neutrophils in the Blood of Pigs that Received a “Microecological System” Alternative to Antibiotics

Abstract

The study was aimed at the identification of a certain link of the nonspecific protection in pigs that enhances its activity during the application of different feeding plans with probiotic “EM-Vita”, creates stable “microecological system”, and provides high natural resistance. Weaned piglets aged 46-53 days were distributed into 3 groups by the method of analog pairs: Group I – control group, Group 2 and 3 – test groups that received even doses of the drug but at different intervals. It was established that in 2 months, pigs that received “EM-Vita” by both schemes had expressed increase in the level of nonspecific protection due to a general increase in the neutrophil count and their fractions capable of both oxygen-dependent microbicide activity and enhanced activity of this process. The application of the drug by one of the schemes provided the creation of the adaptive reserve of neutrophils that exert adsorptive activity, by the other scheme – the increase in the synthesis of cationic proteins. Thus, the periodicity of the application of probiotic “EM-Vita” significantly influences on the status of neutrophils by selective activation of different protective systems.

 Keywords: blood, neutrophils, Lactobacillus plantarum, antibiotic replacement.