ANALYTICAL STUDY ON SOLID PHASE ORGANIC SYNTHESIS AND ITS APPLICATIONS

Abstract

Solid-stage organic synthesis (SPOS) and catalysis have gained driving force after the original revelation of Merrifield's solid-stage peptide synthesis and furthermore due to wide applicability in combinatorial and high throughput science. Countless organic, inorganic, or organic-inorganic half and half materials have been employed as polymeric solid backings to advance or catalyze different organic responses. This survey is aimed to feature probably the most significant uses of these promising materials in organic synthesis. The reason for this survey is to build attention to the wide scope of valuable transformations which can be practiced utilizing solid-bolstered reagents. This audit is aimed to feature the absolute most significant uses of these promising materials in organic synthesis.