Coronavirus: A Review in to the Genome, Origin, Replication, Antibody and Diagnosis of COVID-19.

Abstract

Genome sequences have shown that this coronavirus is related to otherknown coronaviruses, such as two human coronavirus, HCoV-OC43 and HCoV-229E.Coronaviruses are composed of genetic material surrounded by a round envelope that has protein spikes on the outside that resemble the spikes on a crown, the metal headgear worn by many monarchs across the world, WHO explained in a video. “Crown” in Latin is “corona,” hence the name coronavirus.The coronavirus interferes with the peptides in the receptor organism, and that is why many viruses use α-coronavirus aminopeptidase N (APN) as their receptors, and SARS-CoV and HCoV-NL63 use the angiotensin-converting enzyme 2 (ACE2) as their receptors, enter the MHV through CEACAM1, and bind the newly identified MERS-CoV to dipeptidyl-peptidase 4 (DPP4) to enter human cells.